
Slow-release Oral Morphine as MOUD: Used Internationally but Why Not the USA?
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Slow-release Oral Morphine as MOUD: Used Internationally but Why Not the USA?
Recorded: Thursday, April 13, 2023 to Sunday, April 16, 2023
On-Demand Session
Overview
This 75-minute on-demand session from the ASAM 54th Annual Conference addresses the pharmacology and clinical evidence for the use of slow-release oral morphine for treatment of opioid use disorder.
Synthetic opioids and the challenges they bring to the initiation of medications for opioid use disorder are clear. Approaches using slow-release oral morphine (SROM) are used outside the USA. This session discusses its clinical use during methadone inductions, switching from methadone to buprenorphine, and as monotherapy for OUD. We review the international evidence and ongoing clinical trials in North America. Participants will come away of knowledge of a new potential treatment to improve OUD care in the age of fentanyl.
The target audience for this intermediate level session includes physicians, nurse practitioners, physician assistants, other clinicians, researchers, residents, fellows, students, and counselors.
This session addresses the following ACGME Competencies: Patient Care and Procedural Skills, Medical Knowledge, Practice-based Learning and Improvement, Systems-based Practice
This session addresses the following IOM Competencies:Provide patient-centered care, Work in interdisciplinary teams, Employ evidence-based practice
Learning Objectives
Upon completion, learners will be able to:
- describe the pharmacology and clinical evidence for the use of slow-release oral morphine for treatment of opioid use disorder.
- demonstrate knowledge about the clinical evidence for the use of slow-release oral morphine in methadone inductions, MOUD switches to buprenorphine, and as monotherapy for OUD.
- describe the regulatory and policy issues that impact the use of slow-release oral morphine in the USA.
Registration Rates
Rate Description | Rate |
ASAM Member | $29 |
Non-Member | $39 |
Associate Member | $19 |
Resident Member* | $19 |
Student Member* | $19 |
*Residents, Fellows-in-training, Interns, and Students must join ASAM to receive a discounted registration rate. Click here to become an ASAM member. National and Chapter membership dues apply. There is no charge for Students to become a Member, but verification of student status is required.
Membership Question? Call ASAM at 1.301.656.3920, email us, or view the ASAM website for more information.
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Registration Deadline: 05/15/2026
Session Instructions
- Click on the Contents tab to watch the on-demand recording.
- Click Complete Post Test to answer multiple choice questions. Participants will have 10 attempts to pass and must answer 4 out of 5 questions correctly.
- Click Complete Evaluation to provide valuable activity feedback. Scroll down on all questions as there may be answer options that expand past the size of the window.
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Jeremy Weleff, DO
Addiction Psychiatry Fellow
Yale University School of Medicine
Jeremy Weleff, DO is an addiction psychiatry fellow at Yale University in New Haven, Connecticut, and a research fellow at the Cleveland Clinic in Cleveland, Ohio. He completed his psychiatry residency at the Cleveland Clinic and his undergraduate medical education at Michigan State University. His research interests include the social determinants of health, homelessness, addiction, the history of psychiatry, and novel therapeutics.

Gabriela Garcia Vassallo, MD
Assistant Professor
Yale School of Medicine, Department of Psychiatry
Gabriela Garcia Vassallo, MD, is a board-certified Addiction Psychiatrist, Assistant Professor of Psychiatry and VA Site Training Director for Addiction Psychiatry Fellows at the Yale School of Medicine. She is Director of the Opioid Treatment Program at VACTHS which serves a clinical care, education and research mission. Her research and professional interests include expanding access to harm reduction strategies and medication for Opioid Use Disorder and developing interactive, skill based training on the management of Substance Use Disorders.

Andrew Saxon
MD, FASAM
University of Washington School of Medicine, VA Puget Sound Health Care System
Preceding his entry into psychiatry, Dr. Saxon completed an internal medicine internship and worked for 4 years as an emergency room physician. Subsequent to his general psychiatry residency at the University of Washington, Dr. Saxon has more than three decades of experience as a clinical and research addiction psychiatrist. Dr. Saxon is board certified with added qualifications in addiction psychiatry by the American Board of Psychiatry and Neurology. Dr. Saxon sits on the editorial boards of the journals, Drug and Alcohol Dependence and General Hospital Psychiatry and is section editor for substance use disorders for UpToDate. He is a lifetime Distinguished Fellow of the American Psychiatric Association, where he served from 2017-2019 as that organization’s Chair of the Council on Addiction Psychiatry, and a Fellow of the American Society of Addiction Medicine, as well as a member of College on Problems of Drug Dependence and of American Academy of Addiction Psychiatry.
Dr. Saxon’s current research work is supported by the VA, the National Institute on Drug Abuse, and National Institute of Mental Health and involves pharmacotherapies and psychotherapies for alcohol, tobacco, and opioid use disorders, work in co-occurrence of substance use disorders and posttraumatic stress disorder, phenomenology and epidemiology of cannabis use, and treatment of substance use in primary care. He has more than 180 papers published in peer reviewed journals and has done numerous conference presentations.

Mohit Singh, MD, FRCPC, D.ABAM
Addiction Psychiatrist
University of Alberta
Dr. Mohit Singh, MD, FRCPC, D.ABAM is a Clinical Lecturer at the University of Alberta as well as the Associate Program Director for the Addiction Medicine Fellowship program. He obtained his Medical Doctorate (MD) and completed psychiatry residency training at the University of British Columbia. He completed a Forensic Psychiatry fellowship at Yale University, New Haven, USA. Dr. Singh has also obtained a fellowship in Addiction Medicine at the British Columbia Center on Substance Use in Vancouver, Canada. He has considerable experience in conducting assessment, evaluation and treatment of mental health and substance use disorders in outpatient and hospital settings. In addition to his clinical practice, Dr. Singh has served in leadership roles for provincial health organizations.

James Wang, MD, FRCPC
Addiction Medicine Fellow
British Columbia Centre on Substance Use
James Wang, MD, FRCPC is an Addiction Medicine fellow at the British Columbia Centre on Substance Use in Vancouver, Canada. He is a board-certified pediatrician and Adolescent Medicine subspecialist. He completed his post-graduate training at the University of British Columbia and received his medical degree from Cornell University. His academic and clinical interests include youth substance use, youth in the foster care system, adverse childhood experiences, and population health and policy.
CME, CE, CEU and Other Credit Types

ACCME Accreditation Statement
The American Society of Addiction Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
AMA Credit Designation Statement
The American Society of Addiction Medicine designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
NAADAC, the Association for Addiction Professionals
This activity has been approved by the American Society of Addiction Medicine, as a NAADAC Approved Education Provider, for educational credits. NAADAC Provider #295, ASAM is responsible for all aspects of the programming.
California Association for Drug/Alcohol Educators (CAADE)
This educational program is approved by CAADE: #CP40 999 1225.
California Association of DUI Treatment Centers (CADTP)
This educational program is approved by CADTP: #205.
California Consortium of Addiction Programs and Professionals (CCAPP)
This educational program is approved by CCAPP: #OS-20-330-1224.
Continuing Education Credits (CEUs)
Non-physician participants will receive a certificate of attendance upon completion of the activity and an online evaluation confirming their participation. Participants should submit his/her certificate of attendance to their professional organization/institute.
Maintenance of Certification / Continuing Certification Program
American Board of Preventive Medicine (ABPM)
The American Board of Preventive Medicine (ABPM) has approved this activity for 1.25 credits towards ABPM MOC Part II requirements.
American Board of Anesthesiology (ABA)
This activity contributes to the CME component of the American Board of Anesthesiology’s redesigned Maintenance of Certification in Anesthesiology TM (MOCA®) program, known as MOCA 2.0®.
American Board of Pediatrics (ABP)
Successful completion of this CME activity, which includes participation in the activity, with individual assessments of the participant and feedback to the participant, enables the participant to earn 1.25 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABP MOC credit.
American Board of Internal Medicine (ABIM)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn 1.25 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credits.
American Board of Surgery (ABS)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn credit toward the CME and/or Self-Assessment requirements of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.
American Board of Psychiatry and Neurology (ABPN)
Successful completion of this CME activity can be used to satisfy the American Board of Psychiatry and Neurology’s (ABPN) CME requirement for Maintenance of Certification program.
American Board of Addiction Medicine (ABAM)
Successful completion of this activity can be used to satisfy the American Board of Addiction Medicine (ABAM) for Tmoc as credits towards ABAM LLSA Part II requirements.
Royal College of Physicians and Surgeons of Canada (RCPSC)
Royal College Fellows can use participation in Accredited Continuing Medical Education to earn Section 3 Credits.
Disclosure Information
In accordance with disclosure policies of ASAM and the ACCME, the effort is made to ensure balance, independence, objectivity, and scientific rigor in all CME/CE activities. These policies include mitigating all possible relevant financial relationships with ineligible companies for the Planning Committees and Presenters. All activity Planning Committee members and Presenters have disclosed relevant financial relationship information. The ASAM CE Committee has reviewed these disclosures and determined that the relationships are not inappropriate in the context of their respective presentations and are not inconsistent with the educational goals and integrity of the activity.
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