This one-hour, on-demand, journal article-based activity reviews a large cross-sectional study of kratom consumers to evaluate the potential risk for dependency and addiction with kratom consumption and assess the prevalence of kratom use disorder. Up to this time, research about kratom use bas been limited and the prevalence of Kratom Use Disorder (KUD) and indivudual characteristics associated with KUD has not been well understood. The purpose of this study is to improve to gain a clearer clinical understanding of Kratom Use Disorder and better inform the medical community that interacts with patients who consume kratom about the risks of KUD development.

This one-hour, on-demand, journal article-based activity explores original qualitative research on patient perspectives regarding buprenorphine​ discontinuation in the treatment of opioid use disorder (OUD). Little is currently known about the causes of medication discontinuation from the patient perspective. ​Despite buprenorphine and other medications for OUD being the recommended standard care of treatment for OUD and the benefits of positive health and addiction-related outcomes associated with them​, half of patients discontinue medication use in the first year of treatment. Emerging in interviews with patients with OUD treated with buprenorphine were three main themes related to medication discontinuation: health system barriers, adverse effects (or apparent adverse events) associated with the medication, and patient motivations. The purpose of this activity is to better understand patient perspectives around themes of discontinuation and to explore some clinical strategies to enhance patient retention.

This one-hour, on-demand, journal article-based activity details an observational study exploring the relationship between higher first 30-day buprenorphine doses and subsequent rates of opioid-involved overdose death and death from all other causes. The study provides evidence that higher initial doses of buprenorphine are associated with lower mortality rates, supporting the benefits of higher dosing in MOUD treatment. Its findings may inform and improve current clinical practice standards, enhancing patient safety and reducing mortality.

This one-hour, on-demand, journal article-based activity that reviews a recent study that examines death certificate data to assess the staggering increase in overdose death rates among Black and Indigenous women in Wisconsin from 2018 to 2020. According to the study, Wisconsin overdose deaths in this population increased 11-fold from 2000 to 2020, with over 1,200 deaths in 2020.

This one-hour, on-demand, journal article-based activity discusses original research on naloxone ​dosing for prevention of return to use in people with opioid use disorder. It examines the relationship between plasma levels of extended-release naltrexone (XR-NTX) and subjective responses to opioids in individuals with opioid use disorder (OUD), highlighting the importance of maintaining therapeutic naltrexone (NTX) levels.

This one-hour, on-demand, journal article-based activity compares characteristics of participants who reported using xylazine to those who reported not using xylazine in the past 12 months. Data from the National HIV Behavioral Surveillance Survey among persons who inject drugs (PWIDs) in Philadelphia was reviewed to better identify individuals at risk and inform patients and clinicians about xylazine risk factors.

This one-hour, on-demand, journal article-based activity considers the implementation challenges posed when methadone is dispensed at hospital discharge, per the a recent "72-hour Rule" change.

This one-hour, on-demand, journal article-based activity reviews a commentary on the structural and Interpersonal bias experienced by pregnant and parenting individuals with substance use disorder when engaging with healthcare systems.

This one-hour, on-demand, journal article-based activity examines the use of monthly subcutaneous injectable buprenorphine (XR-Bup) as an option for the treatment of opioid use disorder.

This 1-hour, journal article-based CME activity is based on a large retrospective cohort study examining the long-term cardiovascular outcomes among patients with alcohol use disorder. It sought to determine whether patients with AUD who survived COVID-19 had a significantly higher risk of incident cardiovascular diseases within 12 months than patients with AUD without a history of COVID-19.

This 1-hour journal article-based CME activity is based on a qualitative study that explored perspectives on telehealth-delivered psychotherapy among individuals with AUD. This exploration occurred in the wake of the marked increases in risky alcohol use and rates of AUD, as well as the utilization of virtually delivered healthcare, all of which were precipitated by the Covid-19 pandemic.

This 1-hour, journal article-based CME activity presents six key clinical considerations based on a narrative literature review and expert consensus to specifically address considerations for changes to the clinical practice of treatment of OUD with buprenorphine for individuals using high-potency synthetic opioids (HPSO).

This 1-hour, journal article-based CME activity is based on an overview, meta-analysis, and trial sequential analysis were conducted to evaluate the efficacy and safety of varenicline for smoking cessation.

This one-hour, on-demand, journal article-based CME activity presents the findings of a large retrospective cohort study on the association between prenatal cannabis use and risk of adverse perinatal outcomes, controlling for confounding variables such as polysubstance use and demographic factors.

This one-hour, on-demand, journal article-based CME activity at the effectiveness of a contingency management intervention for alcohol use disorder (AUD) from the standpoint of secondary outcomes reflective of harm reduction, beyond the primary outcome of abstinence.