Pharmacologic Innovations in Alpha-2 Agonist Withdrawal Management in EDs and ICUs
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Register
- Non-Member - $39
- Regular Member - $29
- Retired - $29
- Early Career Physician - $29
- Resident - $19
- Student - $19
- Associate - $19
- ASAM Staff - Free!
- International Member - $29
- Emeritus Member - $29
- Provisional Member - $29
- Fellow Member - $29
- Honorary Member - $29
- CRT Member - $29
Pharmacologic Innovations in Alpha-2 Agonist Withdrawal Management in EDs and ICUs
Recorded: Thursday, April 23, 2026 to Sunday, April 26, 2026
On-Demand Session
Overview
This 75-minute on-demand session from the ASAM 57th Annual Conference addresses alpha-2 agonist withdrawal management in emergency and ICU settings, focusing on medetomidine toxicology and emerging treatment strategies.
Join a multidisciplinary panel of experts in emergency medicine, toxicology, addiction medicine and pharmacologists as they explore the evolving landscape of illicit drug adulteration-focusing on the emergence of medetomidine in the fentanyl supply. This session will highlight clinical challenges in diagnosing and managing acute toxicity and withdrawal, with insights into its growing impact on healthcare systems and substance use treatment infrastructure.
The target audience for this Advanced level session includes physicians, nurse practitioners, physician assistants, other clinicians, researchers, residents, fellows, and students.
This session addresses the following ACGME Competencies: Medical Knowledge.
This session addresses the following IPEC Competencies:Teams and Teamwork.
Learning Objectives
Upon completion, learners will be able to:
- Identify toxicosurveillance sources to suggest that medetomidine is contributing to an emerging regional overdose phenomenon.
- Describe the characteristics and pharmacologic management of a medetomidine withdrawal syndrome
- List emerging strategies and innovations considered to mitigate the medetomidine withdrawal syndrome.
Registration Rates
| Rate Description | Rate |
| ASAM Member | $29 |
| Non-Member | $39 |
| Associate Member | $19 |
| Resident Member* | $19 |
| Student Member* | $19 |
*Residents, Fellows-in-training, Interns, and Students must join ASAM to receive a discounted registration rate. Click here to become an ASAM member. National and Chapter membership dues apply. There is no charge for Students to become a Member, but verification of student status is required.
Membership Question? Call ASAM at 1.301.656.3920, email us, or view the ASAM website for more information.
Refunds & Cancellations
All ASAM eLearning Center refund requests must be made in writing to education@asam.org within 90 days of purchase. Those requesting refunds for courses that are in progress will receive partial refunds or e-Learning Center credit. Automatic full refunds will be made for any course with a live-course component that has been cancelled.
Registration Open: 05/25/2026 - 04/25/2029
User Access Closed: 05/25/2029
Course Instructions
- Click on the Contents tab to watch the on-demand recording.
- Click Complete Post Test to answer multiple choice questions. You will have 10 attempts to pass and must answer 4 out of 5 questions correctly.
- Click Complete Evaluation to provide valuable activity feedback. Scroll down on all questions as there may be answer options that expand past the size of the window.
- Click the button Claim Medical Credits in the box titled Claim Credits & Certificate. Choose the type of credit and click submit. Click the button View/Print Certificate to save or print your certificate. You can view/print your certificate at any time by visiting the ASAM eLearning Center, clicking Dashboard, and clicking Transcript/Achievements.
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Dr. Jeanmarie Perrone, MD
Professor of Emergency Medicine and Medical Toxicology, Perelman School of Medicine at the University of Pennsylvania
Jeanmarie Perrone, MD is a Professor in the Department of Emergency Medicine, the Director of the Division of Medical Toxicology and the founding Director of the Center for Addiction Medicine and Policy at the University of Pennsylvania. Dr. Perrone has led numerous investigations and initiatives in opioid stewardship and ED treatment of Opioid Use Disorder (OUD) with buprenorphine. She serves on several regional and national task forces and advisory committees with the State of Pennsylvania, the CDC and FDA addressing judicious opioid use and MOUD treatment access. She has advocated at the state and national level for harm reduction and ED treatment for OUD and is a co-investigator in a 30 site NIDA sponsored trial of ED buprenorphine. Dr. Perrone has been featured in prominent news media including the New York Times, USA Today and National Public Radio and published in the New England Journal of Medicine and JAMA . She has won numerous awards for education and mentorship of students, residents and fellows and is boarded in emergency medicine, medical toxicology and addiction medicine.
No Relevant Financial Disclosures.
Michael J. Lynch
MD
Dr. Michael Lynch is an assistant professor of Emergency Medicine and Pediatrics at the University of Pittsburgh. He is board certified in Emergency Medicine, Medical Toxicology, and Addiction Medicine. Dr. Lynch graduated from the University of Notre Dame and University of Pittsburgh School of Medicine before completing his residency in Emergency Medicine and fellowship in Medical Toxicology at the University of Pittsburgh. Dr. Lynch works in the Emergency Departments at UPMC Presbyterian and Mercy Hospitals. The Toxicology service at UPMC is one of the busiest in the country, seeing patients at 5 Pittsburgh hospitals as well as providing inpatient addiction and telemedicine treatment. Dr. Lynch is the Medical Director of the Pittsburgh Poison Center and of Substance Use Disorder Services at UPMC Health Plan while continuing to serve on the Boards of Directors for the PA College of Emergency Physicians and the American Association of Poison Control Centers. He has implemented naloxone distribution, emergency department buprenorphine induction, as well as inpatient buprenorphine and methadone initiation and maintenance pathways within the UPMC system. Dr. Lynch began the inpatient addiction medicine consultation service at UPMC with a multidisciplinary team, a poison center based withdrawal and addiction treatment support hotline, and, most recently, implemented a telemedicine addiction bridge clinic serving the entire Commonwealth of Pennsylvania. He served on the Pain Management Best Practices Inter-Agency Task Force at the Department of Health and Human Services.
Joseph D'Orazio, MD, FAAEM, FACMT, FASAM, FCPP
Director, Division of Medical Toxicology & Addiction Medicine
Lewis Katz School of Medicine at Temple University
Dr. Joseph D'Orazio is an emergency physician, medical toxicologist, and addiction medicine specialist at the Lewis Katz School of Medicine at Temple University. He cares for Temple patients in a variety of settings, including the emergency department, an inpatient consultative service for addiction medicine and toxicology, the TRUST Clinic (an office-based opioid treatment program), and Begin the Turn (Temple's low-barrier access street-side medicine program). Dr. D’Orazio is a medical toxicologist for the Poison Control Center at Children’s Hospital of Philadelphia and is regarded as a regional expert regarding substance use and substance use disorder treatment in Philadelphia.
Brendan Hart, MD, PhD
Associate Professor of Clinical Emergency Medicine
Temple University
Kory London, MD
Associate Professor, Medical Director, Addiction Provider
Thomas Jefferson University
Andrew Otte, PhD
Research Associate Professor
Purdue University
Accreditation & Credit Designation Statements
Joint Accreditation Statement
In support of improving patient care, the American Society of Addiction Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physicians
The American Society of Addiction Medicine designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nurses
This activity awards 1.25 Nursing contact hours.
Pharmacology Hours
This activity has 1.25 hours that satisfy the requirements for NP and PA Pharmacology Hours.
PAs
ASAM has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1.25 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.25 AAPA Category 1 CME credits. Approval is valid until 05/25/2029. PAs should only claim credit commensurate with the extent of their participation.
Social Workers
As a Jointly Accredited Organization, ASAM is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. Regulatory boards are the final authority on courses accepted for continuing education credit. Social workers completing this course receive 1.25 general continuing education credits.
IPCE Credit
This activity was planned by and for the healthcare team, and learners will receive 1.25 Interprofessional Continuing Education (IPCE) credits for learning and change.
California Association for Drug/Alcohol Educators (CAADE)
This educational program is approved by CAADE: #CP40 999 1225.
California Association of DUI Treatment Centers (CADTP)
This educational program is approved by CADTP: #205.
California Consortium of Addiction Programs and Professionals (CCAPP)
This educational program is approved by CCAPP: # OS-20-330-0227.
Other Professions - Continuing Education Credits (CEUs)
Upon completion of the activity and online evaluation, all other participants may request a certificate of participation. Participants may submit this certificate of participation to their professional organization/institute as documentation for completing this accredited continuing activity.
Maintenance of Certification (MOC) or Continuing Certification Programs (CCP)
This activity is designed to meet the requirements for MOC/CCP for several primary physician boards and for state licensing CME requirements. MOC Credit is only reported and designated for ABA, ABIM, ABP and ABS. By completing the online credit claim and evaluation, the learner permits ASAM to report credits to the appropriate Board. Learn more.
American Board of Anesthesiology (ABA)
This activity offers up to 1.25 CME credits, of which 1.25 credits contribute the patient safety CME component of the American Board of Anesthesiology’s redesigned Maintenance of Certification in AnesthesiologyTM (MOCA®) program, known as MOCA 2.0®. Please consult the ABA website, www.theABA.org, for a list of all MOCA 2.0 requirements.
Maintenance of Certification in Anesthesiology® and MOCA® are registered certification marks of the American Board of Anesthesiology®
American Board of Internal Medicine (ABIM)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.25 Medical Knowledge MOC points and patient safety MOC credit in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
American Board of Pediatrics (ABP)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn up to 1.25 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.
American Board of Preventive Medicine (ABPM)
This activity has been designed to satisfy the Lifelong Professional Development requirements of The American Board of Preventive Medicine’s Continuing Certification (CCP) requirements. These credits are not reported directly to ABPM. Please save your certificate for your records.
American Board of Psychiatry and Neurology (ABPN)
This activity has been designed to satisfy the CME requirements of the American Board of Psychiatry and Neurology’s Continuing Certification (CC) requirements. These credits are not reported directly to ABPN. Please save your certificate for your records.
American Board of Surgery (ABS)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn credit toward the CME requirement of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.
Royal College of Physicians and Surgeons of Canada (RCPSC)
The Royal College of Physicians and Surgeons of Canada will recognize activities registered for CME for MOC as meeting the requirements for Royal College MOC Program Section 3 (Self-Assessment Programs) credits. Visit CME that Counts for Royal College MOC for more information.
Disclosure Information
In accordance with the disclosure policies of ASAM and Joint Accreditation, the effort is made to ensure balance, independence, objectivity, and scientific rigor in all accredited continuing education activities. These policies include identifying and mitigating all relevant financial relationships with ineligible companies for those involved in the creation and dissemination of accredited continuing education. Click here to view the full disclosure listing.
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