Effectiveness of Extended-Release Buprenorphine in OUD: Results from NIDA CTN Studies
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Effectiveness of Extended-Release Buprenorphine in OUD: Results from NIDA CTN Studies
Recorded: Thursday, April 23, 2026 to Sunday, April 26, 2026
On-Demand Session
Overview
This 75-minute on-demand session from the ASAM 57th Annual Conference addresses extended-release buprenorphine effectiveness in OUD, presenting NIDA CTN study results for pregnant patients and emergency department settings.
Presentations from two large, HEAL-funded, NIDA CTN multi-site trials: 1) The Medication Treatment for Opioid-dependent Expecting Mothers (MOMs) Trial showed that participants who received extended-release buprenorphine had significantly higher illicit opioid abstinence during pregnancy and was non-inferior postpartum. 2) The Emergency Department-INitiated bupreNOrphine and VAlidaTIOn Network Trial (ED-INNOVATION) study showed successful implementation of extended release (XR)-BUP in ED patients with untreated OUD; and that it was superior to sublingual (SL) BUP in linkage to care post-ED induction.
The target audience for this Advanced level session includes physicians, nurse practitioners, physician assistants, other clinicians, researchers, residents, fellows, and students.
This session addresses the following ACGME Competencies: Patient Care and Procedural Skills, Medical Knowledge, Systems-based Practice.
This session addresses the following IPEC Competencies: Roles and Responsibilities, Teams and Teamwork.
Learning Objectives
Upon completion, learners will be able to:
- Describe the role of extended-release buprenorphine in the management of pregnant and post-partum women with OUD
- Identify patients with OUD eligible for successful induction on extended-release buprenorphine when they present at ED settings
- Discuss the evidence for the safe and effective use of extended-release buprenorphine in two high risk populations
Registration Rates
| Rate Description | Rate |
| ASAM Member | $29 |
| Non-Member | $39 |
| Associate Member | $19 |
| Resident Member* | $19 |
| Student Member* | $19 |
*Residents, Fellows-in-training, Interns, and Students must join ASAM to receive a discounted registration rate. Click here to become an ASAM member. National and Chapter membership dues apply. There is no charge for Students to become a Member, but verification of student status is required.
Membership Question? Call ASAM at 1.301.656.3920, email us, or view the ASAM website for more information.
Refunds & Cancellations
All ASAM eLearning Center refund requests must be made in writing to education@asam.org within 90 days of purchase. Those requesting refunds for courses that are in progress will receive partial refunds or e-Learning Center credit. Automatic full refunds will be made for any course with a live-course component that has been cancelled.
Registration Open: 05/25/2026 - 04/25/2029
User Access Closed: 05/25/2029
Course Instructions
- Click on the Contents tab to watch the on-demand recording.
- Click Complete Post Test to answer multiple choice questions. You will have 10 attempts to pass and must answer 4 out of 5 questions correctly.
- Click Complete Evaluation to provide valuable activity feedback. Scroll down on all questions as there may be answer options that expand past the size of the window.
- Click the button Claim Medical Credits in the box titled Claim Credits & Certificate. Choose the type of credit and click submit. Click the button View/Print Certificate to save or print your certificate. You can view/print your certificate at any time by visiting the ASAM eLearning Center, clicking Dashboard, and clicking Transcript/Achievements.
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Geetha A. Subramaniam
MD, DFAPA, DFAACAP
Geetha A. Subramaniam, MD, DFAPA, DFAACAP is the Deputy Director of the Center for Clinical Trials Network, at NIDA. In this role, she has been instrumental in developing research projects in a variety of topic areas, including addressing the prevention of substance abuse in adolescents, prevention and intervention of prescription stimulant misuse in youth. Previously, she was a full-time faculty member in the Division of Child Psychiatry at Johns Hopkins School of Medicine and the Associate Medical Director of Mountain Manor Treatment Center, Baltimore, MD, where she led clinical trials with adolescents with SUD and served as a preceptor to residents and fellows. She distinguished herself as a clinical and research expert in the assessment and treatment of adolescents and young adults with opioid use disorders. She is ABPN certified in General, Child, and Adolescent, and Addiction Psychiatry and a Distinguished Fellow of both the American Psychiatric Association and the American Academy of Child and Adolescent Psychiatry.
No relevant financial disclosures.
Michelle Lofwall, MD, DFAPA, DFASAM
Professor of Behavioral Science & Psychiatry, Medical Director of First Bridge & Straus Clinics
University of Kentucky College of Medicine, Center on Drug and Alcohol Research
Gail D'Onofrio
MD, MS, FACEM, FASAM
Dr. D’Onofrio is Professor and the Inaugural Chair of the Department of Emergency Medicine at the Yale School of Medicine (2009) and Physician-in Chief of Emergency Services at Yale-New Haven Hospital EDs with an annual census of approximately 180,000 patients. Dr. D'Onofrio is also Professor in the School of Public Health in the Department of Chronic Disease Epidemiology. She is boarded in emergency and addiction medicine. Dr. D’Onofrio has extensive experience as a leader, researcher, mentor and educator, and is internationally known for her work in alcohol and other substance use disorders (SUDs) as well as for her research on gender variations in women with ischemic heart disease. Her work (JAMA, 2015) demonstrating that ED-initiated buprenorphine increases engagement in addiction treatment for individuals with OUD, has changed clinical practice, receiving multiple science awards, including awards from the Hazelden Betty Ford Foundation and the Clinical Research Forum.
Dr. D’Onofrio has a long track record of mentoring physician scientists in independent research careers. She is the PI of a NIDA K12 establishing the Yale Drug Use, Addiction and HIV Research Scholars (Yale-DAHRS) program, a Mentored Career Development Program with focused training in prevention and treatment of drug use, addiction, and HIV in general medical settings with scholars in Medicine, Emergency Medicine (EM), Pediatrics, Obstetrics and Gynecology, and Pulmonary Critical Care; and she has mentored numerous EM faculty.
She has received multiple awards including Excellence in Mentoring award from the Association for Medical Education and Research in Substance Abuse (AMERSA 2008), Advancing Women in Emergency Medicine award from the Society of Academic Emergency Medicine (SAEM 2016) and the Academy for Women in Academic Emergency Medicine (AWAEM) Outstanding Department Award for the advancement of women (SAEM 2018). She is also the recipient of the ASAM 2021 R. Brinkley Smithers Distinguished Scientist Award.
Accreditation & Credit Designation Statements
Joint Accreditation Statement
In support of improving patient care, the American Society of Addiction Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
Physicians
The American Society of Addiction Medicine designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Nurses
This activity awards 1.25 Nursing contact hours.
Pharmacology Hours
This activity has 0.25 hour that satisfy the requirements for NP and PA Pharmacology Hours.
PAs
ASAM has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1.25 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.25 AAPA Category 1 CME credits. Approval is valid until 05/25/2029. PAs should only claim credit commensurate with the extent of their participation.
Social Workers
As a Jointly Accredited Organization, ASAM is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. Regulatory boards are the final authority on courses accepted for continuing education credit. Social workers completing this course receive 1.25 general continuing education credits.
IPCE Credit
This activity was planned by and for the healthcare team, and learners will receive 1.25 Interprofessional Continuing Education (IPCE) credits for learning and change.
California Association for Drug/Alcohol Educators (CAADE)
This educational program is approved by CAADE: #CP40 999 1225.
California Association of DUI Treatment Centers (CADTP)
This educational program is approved by CADTP: #205.
California Consortium of Addiction Programs and Professionals (CCAPP)
This educational program is approved by CCAPP: # OS-20-330-0227.
Other Professions - Continuing Education Credits (CEUs)
Upon completion of the activity and online evaluation, all other participants may request a certificate of participation. Participants may submit this certificate of participation to their professional organization/institute as documentation for completing this accredited continuing activity.
Maintenance of Certification (MOC) or Continuing Certification Programs (CCP)
This activity is designed to meet the requirements for MOC/CCP for several primary physician boards and for state licensing CME requirements. MOC Credit is only reported and designated for ABA, ABIM, ABP and ABS. By completing the online credit claim and evaluation, the learner permits ASAM to report credits to the appropriate Board. Learn more.
American Board of Anesthesiology (ABA)
This activity offers up to 1.25 CME credits, of which 1.25 credits contribute the patient safety CME component of the American Board of Anesthesiology’s redesigned Maintenance of Certification in AnesthesiologyTM (MOCA®) program, known as MOCA 2.0®. Please consult the ABA website, www.theABA.org, for a list of all MOCA 2.0 requirements.
Maintenance of Certification in Anesthesiology® and MOCA® are registered certification marks of the American Board of Anesthesiology®
American Board of Internal Medicine (ABIM)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.25 Medical Knowledge MOC points and patient safety MOC credit in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.
American Board of Pediatrics (ABP)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn up to 1.25 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit learner completion information to ACCME for the purpose of granting ABP MOC credit.
American Board of Preventive Medicine (ABPM)
This activity has been designed to satisfy the Lifelong Professional Development requirements of The American Board of Preventive Medicine’s Continuing Certification (CCP) requirements. These credits are not reported directly to ABPM. Please save your certificate for your records.
American Board of Psychiatry and Neurology (ABPN)
This activity has been designed to satisfy the CME requirements of the American Board of Psychiatry and Neurology’s Continuing Certification (CC) requirements. These credits are not reported directly to ABPN. Please save your certificate for your records.
American Board of Surgery (ABS)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn credit toward the CME requirement of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.
Royal College of Physicians and Surgeons of Canada (RCPSC)
The Royal College of Physicians and Surgeons of Canada will recognize activities registered for CME for MOC as meeting the requirements for Royal College MOC Program Section 3 (Self-Assessment Programs) credits. Visit CME that Counts for Royal College MOC for more information.
Disclosure Information
In accordance with the disclosure policies of ASAM and Joint Accreditation, the effort is made to ensure balance, independence, objectivity, and scientific rigor in all accredited continuing education activities. These policies include identifying and mitigating all relevant financial relationships with ineligible companies for those involved in the creation and dissemination of accredited continuing education. Click here to view the full disclosure listing.
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