Wounds, Withdrawal, and Overdose: What to Expect from Xylazine Drug Supply Adulteration
- Non-Member - $39
- Regular Member - $29
- Retired - $29
- Early Career Physician - $29
- Resident - $19
- Student - $19
- Associate - $19
- ASAM Staff - Free!
- International Member - $29
- Emeritus Member - $29
- Provisional Member - $29
- Fellow Member - $29
- Honorary Member - $29
- CRT Member - $29
Wounds, Withdrawal, and Overdose: What to Expect from Xylazine Drug Supply Adulteration
Recorded: Thursday, April 13, 2023 to Sunday, April 16, 2023
This 75-minute on-demand session from the ASAM 54th Annual Conference addresses the pharmacology, toxicology, diagnostic testing, and epidemiology of xylazine in exposures.
This interactive session led by an expert medical toxicology and addiction medicine panel will use didactic content, case-based narrative, review of literature, and panel discussion to review important topics about the emerging xylazine crisis in the US. During the session, the latest data on epidemiology and testing will be presented while experiential data will be used to present cases-based narratives of overdose, withdrawal, and complications such as wound development.
The target audience for this intermediate level session includes physicians, nurse practitioners, physician assistants, other clinicians, researchers, residents, fellows, students, and counselors.
This session addresses the following ACGME Competencies: Medical Knowledge, Practice-based Learning and Improvement
This session addresses the following IOM Competencies:Provide patient-centered care, Employ evidence-based practice
Upon completion, learners will be able to:
- Describe adulteration practices, current trends in drug adulteration, and a look back at historical clusters of adulterants (what's old is new again!)
- Describe the pharmacology, toxicology, diagnostic testing, and epidemiology of xylazine in exposures
- Describe common side effects of xylazine exposure including overdose, withdrawal, and wound development
*Residents, Fellows-in-training, Interns, and Students must join ASAM to receive a discounted registration rate. Click here to become an ASAM member. National and Chapter membership dues apply. There is no charge for Students to become a Member, but verification of student status is required.
Refunds & Cancellations
All ASAM e-Learning Center refund requests must be made in writing to firstname.lastname@example.org within 90 days of purchase. Those requesting refunds for courses that are in progress will receive partial refunds or e-Learning Center credit. Automatic full refunds will be made for any course with a live-course component that has been cancelled.
Registration Deadline: 05/15/2026
- Click on the Contents tab to watch the on-demand recording.
- Click Complete Post Test to answer multiple choice questions. Participants will have 10 attempts to pass and must answer 4 out of 5 questions correctly.
- Click Complete Evaluation to provide valuable activity feedback. Scroll down on all questions as there may be answer options that expand past the size of the window.
- Click the button Claim Medical Credits in the box titled Claim Credits & Certificate. Choose the type of credit and click submit. Click the button View/Print Certificate to save or print your certificate. You can view/print your certificate at any time by visiting the ASAM eLearning Center, clicking Dashboard, and clicking Transcript/Achievements.
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Joseph D'Orazio, MD, FAAEM, FACMT, FASAM, FCPP
Director, Division of Medical Toxicology & Addiction Medicine
Lewis Katz School of Medicine at Temple University
Dr. Joseph D'Orazio is an emergency physician, medical toxicologist, and addiction medicine specialist at the Lewis Katz School of Medicine at Temple University. He cares for Temple patients in a variety of settings, including the emergency department, an inpatient consultative service for addiction medicine and toxicology, the TRUST Clinic (an office-based opioid treatment program), and Begin the Turn (Temple's low-barrier access street-side medicine program). Dr. D’Orazio is a medical toxicologist for the Poison Control Center at Children’s Hospital of Philadelphia and is regarded as a regional expert regarding substance use and substance use disorder treatment in Philadelphia.
Rachel S. Wightman
Rachel S. Wightman, MD is an Assistant Professor in the Department of Emergency Medicine at The Warren Alpert Medical School of Brown University. She is the Director of Toxicology Education at Brown Emergency Medicine and serves as faculty of the Addiction Medicine Fellowship at Brown. She completed medical toxicology fellowship and emergency medicine residency at New York University School of Medicine/ Bellevue Hospital Center. She is board certified in medical toxicology and emergency medicine.
Dr. Wightman’s primary clinical expertise is in the evaluation and management of drug toxicity syndromes in complex medical patients and enhancing medication safety for high-risk drugs. Her scholarly interests focus on evaluation and tracking of emerging drug trends and medications for treatment of opioid use disorder.
Evan S. Schwarz
Evan Schwarz, MD is an Associate Professor of Emergency Medicine and the Medical Toxicology Division Chief at the Washington University School of Medicine. Additionally, he is board certified in Addiction Medicine. He directs the medical toxicology and addiction medicine consultation service as well as their outpatient clinic and organized the Emergency Department buprenorphine treatment program. In addition to his work responsibilities, he is a member of the board of directors for the American College of Medical Toxicology and the Past President President of the Missouri College of Emergency Physicians. He is also a physician consultant for Missouri’s STR and SOR grant and has taught several x-waiver courses.
Dr. Jeanmarie Perrone, MD
Professor of Emergency Medicine and Medical Toxicology, Perelman School of Medicine at the University of Pennsylvania
Jeanmarie Perrone, MD is a Professor in the Department of Emergency Medicine, the Director of the Division of Medical Toxicology and the founding Director of the Center for Addiction Medicine and Policy at the University of Pennsylvania. Dr. Perrone has led numerous investigations and initiatives in opioid stewardship and ED treatment of Opioid Use Disorder (OUD) with buprenorphine. She serves on several regional and national task forces and advisory committees with the State of Pennsylvania, the CDC and FDA addressing judicious opioid use and MOUD treatment access. She has advocated at the state and national level for harm reduction and ED treatment for OUD and is a co-investigator in a 30 site NIDA sponsored trial of ED buprenorphine. Dr. Perrone has been featured in prominent news media including the New York Times, USA Today and National Public Radio and published in the New England Journal of Medicine and JAMA . She has won numerous awards for education and mentorship of students, residents and fellows and is boarded in emergency medicine, medical toxicology and addiction medicine.
CME, CE, CEU and Other Credit Types
ACCME Accreditation Statement
The American Society of Addiction Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
AMA Credit Designation Statement
The American Society of Addiction Medicine designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
NAADAC, the Association for Addiction Professionals
This activity has been approved by the American Society of Addiction Medicine, as a NAADAC Approved Education Provider, for educational credits. NAADAC Provider #295, ASAM is responsible for all aspects of the programming.
California Association for Drug/Alcohol Educators (CAADE)
This educational program is approved by CAADE: #CP40 999 1225.
California Association of DUI Treatment Centers (CADTP)
This educational program is approved by CADTP: #205.
California Consortium of Addiction Programs and Professionals (CCAPP)
This educational program is approved by CCAPP: #OS-20-330-1224.
Continuing Education Credits (CEUs)
Non-physician participants will receive a certificate of attendance upon completion of the activity and an online evaluation confirming their participation. Participants should submit his/her certificate of attendance to their professional organization/institute.
Maintenance of Certification / Continuing Certification Program
American Board of Preventive Medicine (ABPM)
The American Board of Preventive Medicine (ABPM) has approved this activity for 1.25 credits towards ABPM MOC Part II requirements.
American Board of Anesthesiology (ABA)
This activity contributes to the CME component of the American Board of Anesthesiology’s redesigned Maintenance of Certification in Anesthesiology TM (MOCA®) program, known as MOCA 2.0®.
American Board of Pediatrics (ABP)
Successful completion of this CME activity, which includes participation in the activity, with individual assessments of the participant and feedback to the participant, enables the participant to earn 1.25 MOC points in the American Board of Pediatrics’ (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABP MOC credit.
American Board of Internal Medicine (ABIM)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn 1.25 Medical Knowledge MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credits.
American Board of Surgery (ABS)
Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn credit toward the CME and/or Self-Assessment requirements of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.
American Board of Psychiatry and Neurology (ABPN)
Successful completion of this CME activity can be used to satisfy the American Board of Psychiatry and Neurology’s (ABPN) CME requirement for Maintenance of Certification program.
American Board of Addiction Medicine (ABAM)
Successful completion of this activity can be used to satisfy the American Board of Addiction Medicine (ABAM) for Tmoc as credits towards ABAM LLSA Part II requirements.
Royal College of Physicians and Surgeons of Canada (RCPSC)
Royal College Fellows can use participation in Accredited Continuing Medical Education to earn Section 3 Credits.
In accordance with disclosure policies of ASAM and the ACCME, the effort is made to ensure balance, independence, objectivity, and scientific rigor in all CME/CE activities. These policies include mitigating all possible relevant financial relationships with ineligible companies for the Planning Committees and Presenters. All activity Planning Committee members and Presenters have disclosed relevant financial relationship information. The ASAM CE Committee has reviewed these disclosures and determined that the relationships are not inappropriate in the context of their respective presentations and are not inconsistent with the educational goals and integrity of the activity.
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